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L-Arginine – How does it work? Effectiveness, Side-Effects, Precautions, And Warnings


L-arginine is a chemical component called an “amino acid.” It is obtained from food and is necessary for the body to make protein. Basically, L-Arginine is present in red meat, fish, poultry, and dairy products. And also, it can be made in the laboratory and used as a Medicine.

L-Arginine is used for chest pain (Angina), narrowing of the blood vessels causing insufficient blood flow to the extremities (peripheral arterial disease), high blood pressure, erectile dysfunction (ED), a complication of pregnancy characterized by high blood pressure. And also, it is helpful for several conditions, but there is no conclusive scientific evidence to support these other uses.

How does it work?

L-Arginine is changed in the body into a chemical called nitric oxide. Nitric oxide dilates blood vessels, improving blood flow. And also, L-Arginine stimulates the issue of the growth of Hormone, Insulin, and additional substances in the body.

Possibly Effective for:

1. Chest Pain (Angina)

Taking L-arginine reduces symptoms and improves exercise tolerance and quality of life in people with angina. However, L-arginine does not appear to contribute to the dilation of blood vessels that constrict in angina pectoris.

2. Erectile Dysfunction (ED)

A daily intake of 2.5 or 5 grams of L-arginine improves sexual function in men with erectile dysfunction. Basically, lower doses may not be effective. But, there is some preliminary evidence that taking L-arginine with sea pine bark extract and other ingredients may improve the effectiveness of low-dose L-arginine in erectile dysfunction. However, taking L-arginine with erectile dysfunction medications may be more effective than medication alone.

3. High Blood Pressure

There is evidence that taking it can lower blood pressure in healthy people, high blood pressure, and people with mild high blood pressure with or without diabetes.

4. Serious Bowel Disease in Premature Infants (Necrotizing Enterocolitis or NEC)

The addition of L-arginine to the formula appears to prevent inflammation of the digestive tract in premature babies. Moreover, a total of 6 premature babies need arginine to avoid the inflammation of the digestive tract.

5. Narrowing of Blood Vessels causing insufficient Blood Flow to the Extremities (Peripheral Arterial Disease)

Studies show that taking it orally or intravenously for up to eight (8) weeks raises blood flow in persons with peripheral arterial disease. Though, long-term use (up to 6 months) does not improve walking speed or distance in these same individuals.

6. Complication of Pregnancy, expressed in High Blood Pressure and Protein Content in the Urine (Pre-Eclampsia)

Most studies show that L-arginine can lower blood pressure in pregnant women with pre-eclampsia. And also, it appears to protect against pre-eclampsia in pregnant women.

7. High Blood Pressure During Pregnancy

Taking L-arginine intravenously can lower blood pressure in pregnant women who have high blood pressure. Furthermore, it is not clear if it reduces oral stress during pregnancy, but it may reduce the need for blood pressure-lowering medications.

Possibly Ineffective for:

1. Long-term kidney disease (chronic kidney disease or CKD).

Most early research suggests that taking it orally or intravenously does not expand kidney function in most people with kidney disease or kidney failure. However, taking it may improve kidney function and reverse anaemia in older people with anaemia associated with kidney disease.

2. Heart attack

Taking L-arginine does not help prevent a heart attack. It also does not positively affect the treatment of a heart attack after it has occurred. Furthermore, there are concerns that it may be harmful to people after a recent heart attack. Moreover, do not take it if you have recently had a heart attack.

3. High cholesterol

Most studies show that taking L-arginine does not help lower cholesterol levels.

4. Tuberculosis

Adding arginine to standard TB treatment does not improve symptoms or cure the infection.

5. Wound healing

Taking L-arginine does not improve wound healing.

Side Effects

1. Ingestion

L-arginine is POSSIBLY SAFE for most people when taken correctly, for a short time. It can cause some side effects like stomach pain, bloating, diarrhoea, gout, allergies, worsening Asthma, and low blood pressure.

2. Skin application

L-arginine is POSSIBLY SAFE for most people when applied briefly to the skin or used in toothpaste.

3. Inhalation

L-arginine is POSSIBLY SAFE for most people when inhaled in the short term.

When given as a shot: L-arginine is probably safe for maximum people when given as a shot over a short time. Furthermore, the thing can cause some side effects like nausea, vomiting, and blood abnormalities.

Special Warnings and Precautions

1. Pregnancy and Breastfeeding

L-Arginine is possibly safe when taken for a short time during pregnancy. Not enough is known about the long-term use of it during pregnancy or breastfeeding. However, be careful and avoid using.

2. Children

L-arginine is possibly safe for children when taken by mouth in appropriate doses when used in toothpaste, when given by injection (intravenous), or when inhaled. However, it is POSSIBLY SAFE when given by injection (intravenous) in high doses. However, doses that are too high can cause thoughtful side effects in children, including death.

3. Asthma

Inhalation of L-arginine can aggravate airway inflammation. And, if you fight with Asthma and decide to use it, use it with caution.

4. Cirrhosis

L-Arginine should be used with caution in people with Cirrhosis.

5. Low blood pressure

L-arginine can lower blood pressure. IT can be a problem if you already have low blood pressure.

6. Recent heart attack

There is concern that L-arginine may increase the risk of death after a heart attack, especially in the elderly. If you have recently obligated a heart attack, do not take it.

7. Kidney disease

L-arginine causes high levels of potassium when used by people with kidney disease. In some cases, this has resulted in life-threatening irregular heartbeats.

8. Surgery

L-arginine can affect blood pressure. However, there is concern that this might interfere with blood pressure control before and after the surgery. However, stop taking it at least two weeks before your planned surgery.

9. Guanidinoacetate Methyltransferase Deficiency

Basically, people with this inherited condition cannot convert arginine and other similar chemicals into creatine. However, to avoid complications associated with this condition, these persons should not take arginine.

Also, find more helpful resources at thewhoblog

10. Herpes

There is concern that L-arginine could make cold sores worse. Furthermore, there is some evidence that it is necessary for the herpes virus to multiply.

Also Read: Melanin – Benefits, Types, What if you do not have enough Melanin?

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